Managing Abstinence

in Newborns

A Family-Centered Program for Infants at Risk for Neonatal Abstinence Syndrome (NAS)

Babies who have been exposed to opioids can develop NAS, resulting in withdrawal symptoms such as feeding difficulties, irritability, sleep issues, and even seizures.

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Our Approach

Caring for Babies With NAS

The MAiN Program provides education, support and other helpful resources to mothers using opioids during pregnancy and after giving birth. Our goal is to help every mom enrolled in MAiN have a positive birth and a healthy baby, even if she is dealing with pain, addiction, mental health issues, or other challenges. 

Watch the video and find out more about how MAiN works.

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A Hospital Program for Newborns at Risk for NAS

MAiN Services

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The baby stays with the mother when possible, or is cared for in the nursery if she isn’t available (for example, when receiving health care or sleeping).

Rooming In

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Mothers in the MAiN program learn to calm their baby in a relaxed environment.

Supportive Care

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We start medication early for babies with NAS symptoms, or at risk of having them.

Early Treatment

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We support babies in the hospital as they safely come off medication.

Medication Weaning

We support families with a range of services, like home visits, breastfeeding support, safety supplies, transportation, and referrals for infant check-ups. 

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A National Trend

The Ongoing Opioid Crisis

85%

percent

Most pregnancies in women who use opioids are not planned (85%).
3600

babies

Around 3,600 babies are born each year in South Carolina to mothers who used opioids during pregnancy.
1

at least

Every day, 1 out of every 156 babies born in South Carolina, is diagnosed with NAS (or opioid withdrawal).
1 in 5

deaths

1 in 5 overdose deaths involved a parent with a dependent child, with most cases being opioids.

MAiN Babies have...

700

Babies

Since 2007, over 700 babies have been served by the MAiN program in South Carolina.
14

Hospitals

The MAiN Hospital Program has been shared with or adopted by fourteen birth hospitals across SC.
Everything you need to know

Resources

SOUTH CAROLINA

Pickens County
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View State and National Resources

Testimonials

  • Mom
    The MAiN program provides so much love and support to those who need it the most. Anything that I needed, whether it as support of something for my baby, they are willing to help!
    Mom
  • Pediatrician
    I think it's been a huge asset to our community, just breaking down the walls of the stigmatization that exists in our community; moms who have gone through program feel better.
    Pediatrician
  • Occupational Therapist
    When babies are in the NICU, the mom is only involved for a few hours at most, but after we implemented MAiN, moms are actually able to touch their babies. We can educate them about decreased stimulation, and developmentally appropriate ways to take care of their babies.
    Occupational Therapist
  • Pediatrician
    Well, you’re getting people who have typically been stigmatized, the opportunity to maintain relationships with them (and the baby) or even family/caregiver with baby, supports keeping moms involved in the social fabric, so they aren’t overlooked, outcast, separated from joys and privileges, viewed as humans with a specific disease rather than addicts
    Pediatrician
  • Doris Street, BS, BSN, RN, CNOR, NE-BC, Nurse Manager
    The MAiN model was successful because our patients really loved the fact that they would be able to stay here with their baby.
    Doris Street, BS, BSN, RN, CNOR, NE-BC, Nurse Manager
    Maternity Services
  • Carly Draddy, MD

    Main encourages moms to take care of the babies and start bonding with the baby.

    Carly Draddy, MD
    Pediatric Hospital
  • Ann Bolt, BSN, RNC-LRN, Charge Nurse,

    MAiN is giving parents more autonomy with their children.

    Ann Bolt, BSN, RNC-LRN, Charge Nurse,
    Level II Nursery
Check out the latest news and events with MAiN

What's happening

MAiN Babies SC
MAiN Babies SCSaturday, December 6th, 2025 at 6:07pm
Having a baby is just the beginning of your journey, and your health matters just as much after you give birth. MAiN supports you after delivery, too, with resources for your recovery and well-being.

🔹 Services we offer after you give birth:

✔️ Help scheduling the appointments you and your baby need
✔️ Infant care & safety supplies
✔️ Help connecting with community resources, like diaper banks, transportation, job placement training, childcare, and more

📍 Visit mainbabies.org (http://mainbabies.org/) to learn more.

#PregnancyHealth #OpioidRecovery #EndAddictionStigma #MaternalCare #HealthyPregnancy
MAiN Babies SC
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MAiN Babies SC
MAiN Babies SCFriday, December 5th, 2025 at 1:19pm
Our goal is to keep mothers and babies healthy and together.

🔗 Learn more: mainbabies.org (http://mainbabies.org/)

#PregnancyHealth #OpioidRecovery #EndAddictionStigma #MaternalCare #HealthyPregnancy
MAiN Babies SC
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MAiN Babies SC
MAiN Babies SCWednesday, December 3rd, 2025 at 5:00pm
We believe that every woman deserves a healthy pregnancy and are here to help. Swipe to explore our three stages of care in the MAiN journey. If you are pregnant, taking opioids, and in need of care, visit our website and enroll today! 💙

#PregnancyHealth #OpioidRecovery #EndAddictionStigma #MaternalCare #HealthyPregnancy
MAiN Babies SC
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