Managing Abstinence
in Newborns
A Family-Centered Program for Infants at Risk for Neonatal Abstinence Syndrome (NAS)
Babies who have been exposed to opioids can develop NAS, resulting in withdrawal symptoms such as feeding difficulties, irritability, sleep issues, and even seizures.
Our Approach
Caring for Babies With NAS
The MAiN Program provides education, support and other helpful resources to mothers using opioids during pregnancy and after giving birth. Our goal is to help every mom enrolled in MAiN have a positive birth and a healthy baby, even if she is dealing with pain, addiction, mental health issues, or other challenges.
Watch the video and find out more about how MAiN works.
A National Trend
The Ongoing Opioid Crisis
85%
percent
Most pregnancies in women who use opioids are not planned (85%).
3600
babies
Around 3,600 babies are born each year in South Carolina to mothers who used opioids during pregnancy.
1
at least
Every day, 1 out of every 156 babies born in South Carolina, is diagnosed with NAS (or opioid withdrawal).
1 in 5
deaths
1 in 5 overdose deaths involved a parent with a dependent child, with most cases being opioids.
MAiN Babies have...
700
Babies
Since 2007, over 700 babies have been served by the MAiN program in South Carolina.
14
Hospitals
The MAiN Hospital Program has been shared with or adopted by fourteen birth hospitals across SC.
Everything you need to know
Resources
SOUTH CAROLINA
Pickens County
Testimonials
We’re proud to have been named a winner of the South Carolina Public Health Association's 2026 Voice of Public Health Award for our work to provide the Managing Abstinence in Newborns program, or MAiN, a family-centered program for infants at risk for opioid withdrawal.
We collaborate with Clemson University, Prisma Health and the South Carolina Opioid Recovery Fund to help the 3,600 babies born each year in South Carolina to mothers who used opioids during pregnancy.
MAiN Nurse Navigators provide guidance, support, education and connections to services for those mothers. Anyone interested in connecting with a MAiN Babies SC Nurse Navigator can simply call 864-870-7419 or email erika.massey@anmed.org to enroll or ask questions. The Nurse Navigator will make contact for next steps, like a care plan, hospital plan, breastfeeding support, treatment and recovery, community resources, and ways that family can be involved.
#BetterStartsHere
We collaborate with Clemson University, Prisma Health and the South Carolina Opioid Recovery Fund to help the 3,600 babies born each year in South Carolina to mothers who used opioids during pregnancy.
MAiN Nurse Navigators provide guidance, support, education and connections to services for those mothers. Anyone interested in connecting with a MAiN Babies SC Nurse Navigator can simply call 864-870-7419 or email erika.massey@anmed.org to enroll or ask questions. The Nurse Navigator will make contact for next steps, like a care plan, hospital plan, breastfeeding support, treatment and recovery, community resources, and ways that family can be involved.
#BetterStartsHere
What's happening